Association of Genetic Mutations in Plasmodium vivax dhfr with Resistance to Sulfadoxine-Pyrimethamine: Geographical and Clinical Correlates

Mutations in the Plasmodium falciparum gene (dhfr) encoding dihydrofolate reductase are associated with resistance to antifols. Plasmodium vivax, the more prevalent malaria parasite in Asia and the Americas, is considered antifol resistant. Functional polymorphisms in the dhfr gene of P. vivax (pvdh...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Imwong, Mallika, Pukrittakayamee, Sasithon, Looareesuwan, Sornchai, Pasvol, Geoffrey, Poirreiz, Jean, White, Nicholas J., Snounou, Georges
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2001
Soggetti:	Mechanisms of Resistance
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90792/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11600366/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.11.3122-3127.2001
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