Association of Genetic Mutations in Plasmodium vivax dhfr with Resistance to Sulfadoxine-Pyrimethamine: Geographical and Clinical Correlates

Mutations in the Plasmodium falciparum gene (dhfr) encoding dihydrofolate reductase are associated with resistance to antifols. Plasmodium vivax, the more prevalent malaria parasite in Asia and the Americas, is considered antifol resistant. Functional polymorphisms in the dhfr gene of P. vivax (pvdh...

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Bibliografische gegevens

Gepubliceerd in:	Antimicrob Agents Chemother
Hoofdauteurs:	Imwong, Mallika, Pukrittakayamee, Sasithon, Looareesuwan, Sornchai, Pasvol, Geoffrey, Poirreiz, Jean, White, Nicholas J., Snounou, Georges
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	American Society for Microbiology (ASM) 2001
Onderwerpen:	Mechanisms of Resistance
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90792/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11600366/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.11.3122-3127.2001
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