Association of Genetic Mutations in Plasmodium vivax dhfr with Resistance to Sulfadoxine-Pyrimethamine: Geographical and Clinical Correlates

Mutations in the Plasmodium falciparum gene (dhfr) encoding dihydrofolate reductase are associated with resistance to antifols. Plasmodium vivax, the more prevalent malaria parasite in Asia and the Americas, is considered antifol resistant. Functional polymorphisms in the dhfr gene of P. vivax (pvdh...

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Autors principals: Imwong, Mallika, Pukrittakayamee, Sasithon, Looareesuwan, Sornchai, Pasvol, Geoffrey, Poirreiz, Jean, White, Nicholas J., Snounou, Georges
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
Matèries:
Mechanisms of Resistance
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC90792/
https://ncbi.nlm.nih.gov/pubmed/11600366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.11.3122-3127.2001
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