In Vitro Activity of ABT-773 against Legionella pneumophila, Its Pharmacokinetics in Guinea Pigs, and Its Use to Treat Guinea Pigs with L. pneumophila Pneumonia
The activity of ABT-773 was studied against extracellular and intracellular Legionella pneumophila and for the treatment of guinea pigs with L. pneumophila pneumonia. The ABT-773 MIC at which 50% of isolates are inhibited (MIC(50)) for 20 different Legionella sp. strains was 0.016 μg/ml, whereas the...
Shranjeno v:
| izdano v: | Antimicrob Agents Chemother |
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| Principais autores: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology (ASM)
2001
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90717/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11557455/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.10.2685-2690.2001 |
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