In Vitro Activity of ABT-773 against Legionella pneumophila, Its Pharmacokinetics in Guinea Pigs, and Its Use to Treat Guinea Pigs with L. pneumophila Pneumonia

The activity of ABT-773 was studied against extracellular and intracellular Legionella pneumophila and for the treatment of guinea pigs with L. pneumophila pneumonia. The ABT-773 MIC at which 50% of isolates are inhibited (MIC(50)) for 20 different Legionella sp. strains was 0.016 μg/ml, whereas the...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Edelstein, Paul H., Higa, F., Edelstein, Martha A. C.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Experimental Therapeutics
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90717/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11557455/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.10.2685-2690.2001
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!