In vitro activity of sparfloxacin (CI-978; AT-4140) for clinical Legionella isolates, pharmacokinetics in guinea pigs, and use to treat guinea pigs with L. pneumophila pneumonia.

The activities of sparfloxacin, ciprofloxacin, and erythromycin for 21 clinical Legionella isolates were determined by agar and broth dilution susceptibility testing and by growth inhibition assays in guinea pig alveolar macrophages (sparfloxacin and ciprofloxacin). All three antimicrobial agents ha...

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Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Edelstein, P H, Edelstein, M A, Weidenfeld, J, Dorr, M B
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1990
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC172010/
https://ncbi.nlm.nih.gov/pubmed/2073101
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