Novel α- and β-Amino Acid Inhibitors of Influenza Virus Neuraminidase

In an effort to discover novel, noncarbohydrate inhibitors of influenza virus neuraminidase we hypothesized that compounds which contain positively charged amino groups in an appropriate position to interact with the Asp 152 or Tyr 406 side chains might be bound tightly by the enzyme. Testing of 300...

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Autors principals: Kati, Warren M., Montgomery, Debra, Maring, Clarence, Stoll, Vincent S., Giranda, Vincent, Chen, Xiaoqi, Laver, W. Graeme, Kohlbrenner, William, Norbeck, Daniel W.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
Matèries:
Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC90693/
https://ncbi.nlm.nih.gov/pubmed/11502530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.9.2563-2570.2001
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