Novel α- and β-Amino Acid Inhibitors of Influenza Virus Neuraminidase

In an effort to discover novel, noncarbohydrate inhibitors of influenza virus neuraminidase we hypothesized that compounds which contain positively charged amino groups in an appropriate position to interact with the Asp 152 or Tyr 406 side chains might be bound tightly by the enzyme. Testing of 300...

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Main Authors: Kati, Warren M., Montgomery, Debra, Maring, Clarence, Stoll, Vincent S., Giranda, Vincent, Chen, Xiaoqi, Laver, W. Graeme, Kohlbrenner, William, Norbeck, Daniel W.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2001
Teme:
Antiviral Agents
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC90693/
https://ncbi.nlm.nih.gov/pubmed/11502530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.9.2563-2570.2001
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