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Novel α- and β-Amino Acid Inhibitors of Influenza Virus Neuraminidase

In an effort to discover novel, noncarbohydrate inhibitors of influenza virus neuraminidase we hypothesized that compounds which contain positively charged amino groups in an appropriate position to interact with the Asp 152 or Tyr 406 side chains might be bound tightly by the enzyme. Testing of 300...

Täydet tiedot

Tallennettuna:
Julkaisussa:Antimicrob Agents Chemother
Päätekijät: Kati, Warren M., Montgomery, Debra, Maring, Clarence, Stoll, Vincent S., Giranda, Vincent, Chen, Xiaoqi, Laver, W. Graeme, Kohlbrenner, William, Norbeck, Daniel W.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 2001
Aiheet:
Antiviral Agents
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90693/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11502530/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.9.2563-2570.2001
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