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In Vitro Susceptibilities of Wild-Type or Drug-Resistant Hepatitis B Virus to (−)-β-d-2,6-Diaminopurine Dioxolane and 2′-Fluoro-5-Methyl-β-l-Arabinofuranosyluracil

Prolonged treatment of chronic hepatitis B virus (HBV) infection with lamivudine ([−]-β-l-2′,3′-dideoxy-3′ thiacytidine) or famciclovir may select for viral mutants that are drug resistant due to point mutations in the polymerase gene. Determining whether such HBV mutants are sensitive to new antivi...

Cur síos iomlán

Sábháilte in:
Sonraí bibleagrafaíochta
Foilsithe in:Antimicrob Agents Chemother
Príomhchruthaitheoirí: Chin, Ruth, Shaw, Tim, Torresi, Joseph, Sozzi, Vittina, Trautwein, Christian, Bock, Thomas, Manns, Michael, Isom, Harriet, Furman, Phil, Locarnini, Stephen
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: American Society for Microbiology (ASM) 2001
Ábhair:
Rochtain ar líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90683/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11502520/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.9.2495-2501.2001
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