In Vitro Susceptibilities of Wild-Type or Drug-Resistant Hepatitis B Virus to (−)-β-d-2,6-Diaminopurine Dioxolane and 2′-Fluoro-5-Methyl-β-l-Arabinofuranosyluracil

Prolonged treatment of chronic hepatitis B virus (HBV) infection with lamivudine ([−]-β-l-2′,3′-dideoxy-3′ thiacytidine) or famciclovir may select for viral mutants that are drug resistant due to point mutations in the polymerase gene. Determining whether such HBV mutants are sensitive to new antivi...

Descrizione completa

Dettagli Bibliografici

Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Chin, Ruth, Shaw, Tim, Torresi, Joseph, Sozzi, Vittina, Trautwein, Christian, Bock, Thomas, Manns, Michael, Isom, Harriet, Furman, Phil, Locarnini, Stephen
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2001
Soggetti:	Antiviral Agents
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90683/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11502520/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.9.2495-2501.2001
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!