In Vitro Susceptibilities of Wild-Type or Drug-Resistant Hepatitis B Virus to (−)-β-d-2,6-Diaminopurine Dioxolane and 2′-Fluoro-5-Methyl-β-l-Arabinofuranosyluracil

Prolonged treatment of chronic hepatitis B virus (HBV) infection with lamivudine ([−]-β-l-2′,3′-dideoxy-3′ thiacytidine) or famciclovir may select for viral mutants that are drug resistant due to point mutations in the polymerase gene. Determining whether such HBV mutants are sensitive to new antivi...

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Detalles Bibliográficos

Publicado en:	Antimicrob Agents Chemother
Autores principales:	Chin, Ruth, Shaw, Tim, Torresi, Joseph, Sozzi, Vittina, Trautwein, Christian, Bock, Thomas, Manns, Michael, Isom, Harriet, Furman, Phil, Locarnini, Stephen
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 2001
Materias:	Antiviral Agents
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90683/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11502520/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.9.2495-2501.2001
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