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Aminoglycoside Resistance with Homogeneous and Heterogeneous Populations of Antibiotic-Resistant Ribosomes

Aminoglycosides bind to rRNA in the small subunit of the bacterial ribosome. Mutations in the decoding region of 16S rRNA confer resistance to specific subsets of aminoglycoside antibiotics. The two major classes of 2-deoxystreptamine aminoglycosides are the 4,5- and the 4,6-disubstituted antibiotic...

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Main Authors: Recht, Michael I., Puglisi, Joseph D.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2001
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC90670/
https://ncbi.nlm.nih.gov/pubmed/11502507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.9.2414-2419.2001
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