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Aminoglycoside Resistance with Homogeneous and Heterogeneous Populations of Antibiotic-Resistant Ribosomes

Aminoglycosides bind to rRNA in the small subunit of the bacterial ribosome. Mutations in the decoding region of 16S rRNA confer resistance to specific subsets of aminoglycoside antibiotics. The two major classes of 2-deoxystreptamine aminoglycosides are the 4,5- and the 4,6-disubstituted antibiotic...

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Bibliografski detalji
Glavni autori: Recht, Michael I., Puglisi, Joseph D.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2001
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC90670/
https://ncbi.nlm.nih.gov/pubmed/11502507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.9.2414-2419.2001
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