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Antiviral Guanosine Analogs as Substrates for Deoxyguanosine Kinase: Implications for Chemotherapy

A highly active form of human recombinant deoxyguanosine kinase (dGK) phosphorylated purine nucleoside analogs active against cytomegalovirus, hepatitis B virus, and human immunodeficiency virus, such as penciclovir, 2′,3′-dideoxyguanosine and 3′-fluoro-2′,3′-dideoxyguanosine. The antiherpesvirus dr...

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Bibliografiske detaljer
Main Authors: Sjöberg, Anita Herrström, Wang, Liya, Eriksson, Staffan
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC90366/
https://ncbi.nlm.nih.gov/pubmed/11181353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.3.739-742.2001
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