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Mechanisms of substrate selectivity for Bacillus anthracis thymidylate kinase

Bacillus anthracis is well known in connection with biological warfare. The search for new drug targets and antibiotics is highly motivated because of upcoming multiresistant strains. Thymidylate kinase is an ideal target since this enzyme is at the junction of the de novo and salvage synthesis of d...

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Библиографические подробности
Главные авторы: Carnrot, Cecilia, Wang, Liya, Topalis, Dimitri, Eriksson, Staffan
Формат: Artigo
Язык:Inglês
Опубликовано: Cold Spring Harbor Laboratory Press 2008
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2525521/
https://ncbi.nlm.nih.gov/pubmed/18523102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.034199.107
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