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Mechanisms of substrate selectivity for Bacillus anthracis thymidylate kinase

Bacillus anthracis is well known in connection with biological warfare. The search for new drug targets and antibiotics is highly motivated because of upcoming multiresistant strains. Thymidylate kinase is an ideal target since this enzyme is at the junction of the de novo and salvage synthesis of d...

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Bibliografiske detaljer
Main Authors: Carnrot, Cecilia, Wang, Liya, Topalis, Dimitri, Eriksson, Staffan
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2525521/
https://ncbi.nlm.nih.gov/pubmed/18523102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.034199.107
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