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Structures of thymidine kinase 1 of human and mycoplasmic origin

Cytosolic thymidine kinase 1, TK1, is a well known cell-cycle-regulated enzyme of importance in nucleotide metabolism as well as an activator of antiviral and anticancer drugs such as 3′-azido-3′-deoxythymidine (AZT). We have now determined the structures of the TK1 family, the human and Ureaplasma...

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Detalhes bibliográficos
Main Authors: Welin, Martin, Kosinska, Urszula, Mikkelsen, Nils-Egil, Carnrot, Cecilia, Zhu, Chunying, Wang, Liya, Eriksson, Staffan, Munch-Petersen, Birgitte, Eklund, Hans
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC539776/
https://ncbi.nlm.nih.gov/pubmed/15611477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0406332102
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