High-Affinity Binding of Silybin Derivatives to the Nucleotide-Binding Domain of a Leishmania tropica P-Glycoprotein-Like Transporter and Chemosensitization of a Multidrug-Resistant Parasite to Daunomycin

In order to overcome the multidrug resistance mediated by P-glycoprotein-like transporters in Leishmania spp., we have studied the effects produced by derivatives of the flavanolignan silybin and related compounds lacking the monolignol unit on (i) the affinity of binding to a recombinant C-terminal...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Pérez-Victoria, José M., Pérez-Victoria, F. Javier, Conseil, Gwenaëlle, Maitrejean, Mathias, Comte, Gilles, Barron, Denis, Di Pietro, Attilio, Castanys, Santiago, Gamarro, Francisco
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2001
Gaiak:
Mechanisms of Action: Physiological Effects
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC90310/
https://ncbi.nlm.nih.gov/pubmed/11158738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.2.439-446.2001
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak