Pharmacological Basis for Concentration-Controlled Therapy with Zidovudine, Lamivudine, and Indinavir

Conventional antiretroviral therapy involves administration of standard fixed doses to adults and adolescents. This approach ignores interindividual variability in pharmacokinetics and results in substantial differences in systemic concentrations among patients. Thus, variability in systemic concent...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Kakuda, Thomas N., Page, Linda M., Anderson, Peter L., Henry, Keith, Schacker, Timothy W., Rhame, Frank S., Acosta, Edward P., Brundage, Richard C., Fletcher, Courtney V.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2001
Schlagworte:	Pharmacology
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90267/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11120972/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.1.236-242.2001
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