Pharmacological Basis for Concentration-Controlled Therapy with Zidovudine, Lamivudine, and Indinavir

Conventional antiretroviral therapy involves administration of standard fixed doses to adults and adolescents. This approach ignores interindividual variability in pharmacokinetics and results in substantial differences in systemic concentrations among patients. Thus, variability in systemic concent...

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Autors principals: Kakuda, Thomas N., Page, Linda M., Anderson, Peter L., Henry, Keith, Schacker, Timothy W., Rhame, Frank S., Acosta, Edward P., Brundage, Richard C., Fletcher, Courtney V.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC90267/
https://ncbi.nlm.nih.gov/pubmed/11120972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.1.236-242.2001
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