Pharmacological Basis for Concentration-Controlled Therapy with Zidovudine, Lamivudine, and Indinavir

Conventional antiretroviral therapy involves administration of standard fixed doses to adults and adolescents. This approach ignores interindividual variability in pharmacokinetics and results in substantial differences in systemic concentrations among patients. Thus, variability in systemic concent...

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Detalhes bibliográficos
Main Authors: Kakuda, Thomas N., Page, Linda M., Anderson, Peter L., Henry, Keith, Schacker, Timothy W., Rhame, Frank S., Acosta, Edward P., Brundage, Richard C., Fletcher, Courtney V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC90267/
https://ncbi.nlm.nih.gov/pubmed/11120972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.1.236-242.2001
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