Pharmacological Basis for Concentration-Controlled Therapy with Zidovudine, Lamivudine, and Indinavir

Conventional antiretroviral therapy involves administration of standard fixed doses to adults and adolescents. This approach ignores interindividual variability in pharmacokinetics and results in substantial differences in systemic concentrations among patients. Thus, variability in systemic concent...

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Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Kakuda, Thomas N., Page, Linda M., Anderson, Peter L., Henry, Keith, Schacker, Timothy W., Rhame, Frank S., Acosta, Edward P., Brundage, Richard C., Fletcher, Courtney V.
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 2001
Sujets:	Pharmacology
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90267/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11120972/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.1.236-242.2001
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