High-Level Fluoroquinolone-Resistant Clinical Isolates of Escherichia coli Overproduce Multidrug Efflux Protein AcrA

Immunoblotting with antibody against AcrA, an obligatory component of the AcrAB multidrug efflux system, showed that this protein was overexpressed by ≥170% in 9 of 10 clinical isolates of Esherichia coli with high-level ciprofloxacin resistance (MICs, ≥32 μg/ml) but not in any of the 15 isolates fo...

Fuld beskrivelse

Bibliografiske detaljer

Udgivet i:	Antimicrob Agents Chemother
Principais autores:	Mazzariol, Annarita, Tokue, Yutaka, Kanegawa, Tiffany M., Cornaglia, Giuseppe, Nikaido, Hiroshi
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2000
Fag:	Mechanisms of Resistance
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90220/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11083655/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.12.3441-3443.2000
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!