High-Level Fluoroquinolone-Resistant Clinical Isolates of Escherichia coli Overproduce Multidrug Efflux Protein AcrA

Immunoblotting with antibody against AcrA, an obligatory component of the AcrAB multidrug efflux system, showed that this protein was overexpressed by ≥170% in 9 of 10 clinical isolates of Esherichia coli with high-level ciprofloxacin resistance (MICs, ≥32 μg/ml) but not in any of the 15 isolates fo...

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Bibliografische gegevens

Gepubliceerd in:	Antimicrob Agents Chemother
Hoofdauteurs:	Mazzariol, Annarita, Tokue, Yutaka, Kanegawa, Tiffany M., Cornaglia, Giuseppe, Nikaido, Hiroshi
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	American Society for Microbiology (ASM) 2000
Onderwerpen:	Mechanisms of Resistance
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90220/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11083655/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.12.3441-3443.2000
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