High-Level Fluoroquinolone-Resistant Clinical Isolates of Escherichia coli Overproduce Multidrug Efflux Protein AcrA
Immunoblotting with antibody against AcrA, an obligatory component of the AcrAB multidrug efflux system, showed that this protein was overexpressed by ≥170% in 9 of 10 clinical isolates of Esherichia coli with high-level ciprofloxacin resistance (MICs, ≥32 μg/ml) but not in any of the 15 isolates fo...
Guardat en:
| Publicat a: | Antimicrob Agents Chemother |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
2000
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90220/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11083655/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.12.3441-3443.2000 |
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