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TEM-72, a New Extended-Spectrum β-Lactamase Detected in Proteus mirabilis and Morganella morganii in Italy

A new natural TEM-2 derivative, named TEM-72, was identified in a Proteus mirabilis strain and in a Morganella morganii strain isolated in Italy in 1999. Compared to TEM-1, TEM-72 contains the following amino acid substitutions: Q39K, M182T, G238S, and E240K. Kinetic analysis showed that TEM-72 exhi...

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Gepubliceerd in:Antimicrob Agents Chemother
Hoofdauteurs: Perilli, Mariagrazia, Segatore, Bernardetta, Rosaria De Massis, Maria, Riccio, Maria Letizia, Bianchi, Ciro, Zollo, Alessandro, Rossolini, Gian Maria, Amicosante, Gianfranco
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 2000
Onderwerpen:
Mechanisms of Resistance
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90100/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10952610/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.9.2537-2539.2000
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