Ceftazidime and Aztreonam Resistance in Providencia stuartii: Characterization of a Natural TEM-Derived ExtendedSpectrum β-Lactamase, TEM-60

A plasmid-encoded β-lactamase produced from a clinical strain of Providencia stuartii has been purified and characterized. The gene coding for the β-lactamase was cloned and sequenced. It appears to be a new natural TEM-derived enzyme, named TEM-60. Point mutations (Q39K, L51P, E104K, and R164S) are...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Franceschini, Nicola, Perilli, Mariagrazia, Segatore, Bernardetta, Setacci, Domenico, Amicosante, Gianfranco, Mazzariol, Annarita, Cornaglia, Giuseppe
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1998
Soggetti:	Mechanisms of Resistance
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC105622/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9624494/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.42.6.1459
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