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Interactions of Ofloxacin and Erythromycin with the Multidrug Resistance Protein (MRP) in MRP-Overexpressing Human Leukemia Cells

To investigate interactions between the multidrug resistance protein (MRP) and antimicrobial agents, we examined the effects of 12 agents on vincristine sensitivity and efflux of the calcein acetoxy-methyl ester (calcein-AM) of a MRP substrate in MRP-overexpressing cells. Only ofloxacin and erythrom...

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書誌詳細
主要な著者: Terashi, Kenji, Oka, Mikio, Soda, Hiroshi, Fukuda, Minoru, Kawabata, Shigeru, Nakatomi, Katsumi, Shiozawa, Ken, Nakamura, Takashi, Tsukamoto, Kazuhiro, Noguchi, Yuji, Suenaga, Mitsuhiro, Tei, Chuwa, Kohno, Shigeru
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2000
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC89936/
https://ncbi.nlm.nih.gov/pubmed/10817732
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