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Difference in Incidence of Spontaneous Mutations between Herpes Simplex Virus Types 1 and 2

Spontaneous mutations within the herpes simplex virus (HSV) genome are introduced by errors during DNA replication. Indicative of the inherent mutation rate of HSV DNA replication, heterogeneous HSV populations containing both acyclovir (ACV)-resistant and ACV-sensitive viruses occur naturally in bo...

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Detalhes bibliográficos
Main Authors: Sarisky, Robert T., Nguyen, Tammy T., Duffy, Karen E., Wittrock, Robert J., Leary, Jeffry J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC89907/
https://ncbi.nlm.nih.gov/pubmed/10817703
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