Difference in Incidence of Spontaneous Mutations between Herpes Simplex Virus Types 1 and 2

Spontaneous mutations within the herpes simplex virus (HSV) genome are introduced by errors during DNA replication. Indicative of the inherent mutation rate of HSV DNA replication, heterogeneous HSV populations containing both acyclovir (ACV)-resistant and ACV-sensitive viruses occur naturally in bo...

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Detalles Bibliográficos

Publicado en:	Antimicrob Agents Chemother
Autores principales:	Sarisky, Robert T., Nguyen, Tammy T., Duffy, Karen E., Wittrock, Robert J., Leary, Jeffry J.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 2000
Materias:	Antiviral Agents
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89907/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10817703/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.6.1524-1529.2000
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