Assessing the contribution of the herpes simplex virus DNA polymerase to spontaneous mutations
BACKGROUND: The thymidine kinase (tk) mutagenesis assay is often utilized to determine the frequency of herpes simplex virus (HSV) replication-mediated mutations. Using this assay, clinical and laboratory HSV-2 isolates were shown to have a 10- to 80-fold higher frequency of spontaneous mutations co...
Kaydedildi:
| Yayımlandı: | BMC Infect Dis |
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| Asıl Yazarlar: | , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
BMC
2002
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC113270/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12019036/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2334-2-7 |
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