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Effect of Fluconazole on the Pharmacokinetics of Doxorubicin in Nonhuman Primates

Antifungal prophylaxis in cancer patients who are undergoing chemotherapy is associated with prolonged neutropenia. We measured the effect of fluconazole on doxorubicin pharmacokinetics in nonhuman primates to determine if neutropenia is related to a pharmacokinetic interaction that delays the clear...

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Autors principals: Warren, Katherine E., McCully, Cynthia M., Walsh, Thomas J., Balis, Frank M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC89824/
https://ncbi.nlm.nih.gov/pubmed/10722523
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