Serum and Cerebrospinal Fluid Pharmacokinetics of Intravenous and Oral Lamivudine in Human Immunodeficiency Virus-Infected Children

We studied the pharmacokinetics of intravenously and orally administered lamivudine at six dose levels ranging from 0.5 to 10 mg/kg of body weight in 52 children with human immunodeficiency virus infection. A two-compartment model with first-order elimination from the central compartment was simulta...

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Detalhes bibliográficos
Main Authors: Mueller, Brigitta U., Lewis, Linda L., Yuen, Geoffrey J., Farley, Maureen, Keller, Amy, Church, Joseph A., Goldsmith, Jonathan C., Venzon, David J., Rubin, Marc, Pizzo, Philip A., Balis, Frank M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1998
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC106021/
https://ncbi.nlm.nih.gov/pubmed/9835513
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