In Vivo Activity and Pharmacokinetics of Ziracin (SCH27899), a New Long-Acting Everninomicin Antibiotic, in a Murine Model of Penicillin-Susceptible or Penicillin-Resistant Pneumococcal Pneumonia

The effectiveness of ziracin (SCH27899), a novel everninomicin, was at first investigated against lethal pneumonia caused by a penicillin-susceptible Streptococcus pneumoniae strain. A single intravenous injection of ziracin at a dose of 60 mg/kg of body weight given at 18 h postinfection protected...

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Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Wang, Erjian, Simard, Marie, Bergeron, Yves, Beauchamp, Denis, Bergeron, Michel G.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2000
Témata:	Experimental Therapeutics
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89806/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10722505/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.4.1010-1018.2000
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