In Vivo Activity and Pharmacokinetics of Ziracin (SCH27899), a New Long-Acting Everninomicin Antibiotic, in a Murine Model of Penicillin-Susceptible or Penicillin-Resistant Pneumococcal Pneumonia

The effectiveness of ziracin (SCH27899), a novel everninomicin, was at first investigated against lethal pneumonia caused by a penicillin-susceptible Streptococcus pneumoniae strain. A single intravenous injection of ziracin at a dose of 60 mg/kg of body weight given at 18 h postinfection protected...

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發表在:	Antimicrob Agents Chemother
Principais autores:	Wang, Erjian, Simard, Marie, Bergeron, Yves, Beauchamp, Denis, Bergeron, Michel G.
格式:	Artigo
語言:	Inglês
出版:	American Society for Microbiology (ASM) 2000
主題:	Experimental Therapeutics
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89806/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10722505/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.4.1010-1018.2000
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