Efficacy of FK463, a New Lipopeptide Antifungal Agent, in Mouse Models of Pulmonary Aspergillosis

The efficacy of FK463, a novel water-soluble lipopeptide, was evaluated in mouse models of pulmonary aspergillosis and was compared with that of amphotericin B (AMPH-B). In the pulmonary aspergillosis models induced by intranasal inoculation, FK463 exhibited good efficacy, with 50% effective doses i...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Matsumoto, Satoru, Wakai, Yoshimi, Nakai, Toru, Hatano, Kazuo, Ushitani, Tomoe, Ikeda, Fumiaki, Tawara, Shuichi, Goto, Toshio, Matsumoto, Fumio, Kuwahara, Shogo
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Experimental Therapeutics
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89736/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10681328/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.3.619-621.2000
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