Role of the PDR Gene Network in Yeast Susceptibility to the Antifungal Antibiotic Mucidin
Yeast strains disrupted in the PDR1, PDR3, or PDR5 gene, but not in SNQ2, exhibited higher sensitivity to mucidin (strobilurin A) than did the isogenic wild-type strains. Different gain-of-function mutations in the PDR1 and PDR3 genes rendered yeast mutants resistant to this antibiotic. Mucidin indu...
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| Published in: | Antimicrob Agents Chemother |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Microbiology (ASM)
2000
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89695/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10639374/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.2.418-420.2000 |
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