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Role of the PDR Gene Network in Yeast Susceptibility to the Antifungal Antibiotic Mucidin

Yeast strains disrupted in the PDR1, PDR3, or PDR5 gene, but not in SNQ2, exhibited higher sensitivity to mucidin (strobilurin A) than did the isogenic wild-type strains. Different gain-of-function mutations in the PDR1 and PDR3 genes rendered yeast mutants resistant to this antibiotic. Mucidin indu...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Michalkova-Papajova, Dana, Obernauerova, Margita, Subik, Julius
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89695/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10639374/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.2.418-420.2000
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