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Unusual Antimicrotubule Activity of the Antifungal Agent Spongistatin 1

Spongistatin 1, a macrocyclic lactone from the marine sponge Hyrtios erecta, has broad-spectrum antifungal activity. Since this compound is a potent antimicrotubule agent in mammalian cells, we examined its effects on the filamentous fungus Aspergillus nidulans to determine if its antifungal effects...

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Hlavní autoři: Ovechkina, Yulia Y., Pettit, Robin K., Cichacz, Zbigniew A., Pettit, George R., Oakley, Berl R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 1999
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC89403/
https://ncbi.nlm.nih.gov/pubmed/10428925
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