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A Nine-Codon Deletion Mutation in the Cytomegalovirus UL97 Phosphotransferase Gene Confers Resistance to Ganciclovir

A deletion mutation (codons 595 to 603) in the cytomegalovirus (CMV) UL97 gene was recently reported after sequence analysis of leukocyte DNA from a patient receiving ganciclovir. The corresponding viral phenotype was examined by transfer of this mutation to a laboratory CMV strain (strain Towne). T...

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Bibliografske podrobnosti
izdano v:Antimicrob Agents Chemother
Principais autores: Chou, Sunwen, Meichsner, Camie L.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2000
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89650/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10602745/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.1.183-185.2000
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