Carbapenem Derivatives as Potential Inhibitors of Various β-Lactamases, Including Class B Metallo-β-Lactamases

A variety of 1β-methylcarbapenem derivatives were screened to identify inhibitors of IMP-1 metallo-β-lactamase, a class B β-lactamase, in an automated microassay system using nitrocefin as a substrate. The structure–inhibitory-activity relationship study revealed that three types of 1β-methylcarbape...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Nagano, Rie, Adachi, Yuka, Imamura, Hideaki, Yamada, Koji, Hashizume, Terutaka, Morishima, Hajime
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 1999
Témata:
Susceptibility
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC89507/
https://ncbi.nlm.nih.gov/pubmed/10508031
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky