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In Vitro Potentiation of Carbapenems with ME1071, a Novel Metallo-β-Lactamase Inhibitor, against Metallo-β-Lactamase- Producing Pseudomonas aeruginosa Clinical Isolates

ME1071, a maleic acid derivative, is a novel specific inhibitor for metallo-β-lactamases (MBL). In this study, the potentiation of ME1071 in combination with several β-lactams was evaluated using MBL-producing Pseudomonas aeruginosa isolates. The rates of susceptibility of MBL producers to carbapene...

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Bibliographic Details
Main Authors: Ishii, Yoshikazu, Eto, Maki, Mano, Yoko, Tateda, Kazuhiro, Yamaguchi, Keizo
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2934957/
https://ncbi.nlm.nih.gov/pubmed/20606062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01397-09
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