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In Vitro Activities of Novel trans-3,5-Disubstituted Pyrrolidinylthio-1β-Methylcarbapenems with Potent Activities against Methicillin-Resistant Staphylococcus aureus and Pseudomonas aeruginosa

The in vitro activities of the novel 1β-methylcarbapenems J-111,225, J-114,870, and J-114,871, which have a structurally unique side chain that consists of a trans-3,5-disubstituted 5-arylpyrrolidin-3-ylthio moiety at the C-2 position, were compared with those of reference antibiotics. Among isolate...

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Main Authors: Nagano, Rie, Shibata, Kaneyoshi, Adachi, Yuka, Imamura, Hideaki, Hashizume, Terutaka, Morishima, Hajime
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC89716/
https://ncbi.nlm.nih.gov/pubmed/10681308
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