Characterization and Quantitation of the Pharmacodynamics of Fluconazole in a Neutropenic Murine Disseminated Candidiasis Infection Model
We determined the pharmacodynamic parameter and the magnitude of that parameter that was predictive of the efficacy of fluconazole in the treatment of disseminated candidiasis. We used a neutropenic murine model of disseminated Candida albicans infection to characterize the time course of activity o...
Guardado en:
| Publicado en: | Antimicrob Agents Chemother |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology (ASM)
1999
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89432/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10471550/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.9.2116 |
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