Characterization and Quantitation of the Pharmacodynamics of Fluconazole in a Neutropenic Murine Disseminated Candidiasis Infection Model

We determined the pharmacodynamic parameter and the magnitude of that parameter that was predictive of the efficacy of fluconazole in the treatment of disseminated candidiasis. We used a neutropenic murine model of disseminated Candida albicans infection to characterize the time course of activity o...

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Bibliographic Details
Main Authors: Andes, D., van Ogtrop, M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC89432/
https://ncbi.nlm.nih.gov/pubmed/10471550
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