A Family of Insertion Mutations between Codons 67 and 70 of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Confer Multinucleoside Analog Resistance

To investigate the occurrence of multinucleoside analog resistance during therapy failure, we surveyed the drug susceptibilities and genotypes of nearly 900 human immunodeficiency virus type 1 (HIV-1) samples. For 302 of these, the 50% inhibitory concentrations of at least four of the approved nucle...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Larder, B. A., Bloor, S., Kemp, S. D., Hertogs, Kurt, Desmet, R. L., Miller, V., Sturmer, M., Staszewski, S., Ren, J., Stammers, D. K., Stuart, D. I., Pauwels, R.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1999
Soggetti:	Antiviral Agents
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89398/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10428920/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.8.1961
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