A Family of Insertion Mutations between Codons 67 and 70 of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Confer Multinucleoside Analog Resistance

To investigate the occurrence of multinucleoside analog resistance during therapy failure, we surveyed the drug susceptibilities and genotypes of nearly 900 human immunodeficiency virus type 1 (HIV-1) samples. For 302 of these, the 50% inhibitory concentrations of at least four of the approved nucle...

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הוצא לאור ב:	Antimicrob Agents Chemother
Principais autores:	Larder, B. A., Bloor, S., Kemp, S. D., Hertogs, Kurt, Desmet, R. L., Miller, V., Sturmer, M., Staszewski, S., Ren, J., Stammers, D. K., Stuart, D. I., Pauwels, R.
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Society for Microbiology (ASM) 1999
נושאים:	Antiviral Agents
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89398/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10428920/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.8.1961
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