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Retroviral recombination can lead to linkage of reverse transcriptase mutations that confer increased zidovudine resistance.

Genetic recombination between viral genomes has been shown to contribute to the generation of genetic diversity during retrovirus infections. The role of recombination in the development of human immunodeficiency virus type 1 (HIV-1) zidovudine resistance was investigated as a possible cause of the...

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Detalhes bibliográficos
Main Authors: Kellam, P, Larder, B A
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC188627/
https://ncbi.nlm.nih.gov/pubmed/7529334
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