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Retroviral recombination can lead to linkage of reverse transcriptase mutations that confer increased zidovudine resistance.

Genetic recombination between viral genomes has been shown to contribute to the generation of genetic diversity during retrovirus infections. The role of recombination in the development of human immunodeficiency virus type 1 (HIV-1) zidovudine resistance was investigated as a possible cause of the...

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Hlavní autoři: Kellam, P, Larder, B A
Médium: Artigo
Jazyk:Inglês
Vydáno: 1995
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC188627/
https://ncbi.nlm.nih.gov/pubmed/7529334
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