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Class C β-Lactamases Operate at the Diffusion Limit for Turnover of Their Preferred Cephalosporin Substrates
It has been suggested that class C β-lactamases have evolved to carry out a metabolic reaction other than hydrolysis of β-lactam antibiotics. It is demonstrated in the present study that the class C β-lactamase from Enterobacter cloacae P99 has reached the diffusion limit in its ability to hydrolyze...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
1999
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC89354/ https://ncbi.nlm.nih.gov/pubmed/10390233 |
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