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Three Decades of the Class A β-Lactamase Acyl-Enzyme

The discovery that the mechanism of β-lactam hydrolysis catalyzed by the class A (active site serine-dependent) β-lactamases proceeds via an acyl-enzyme intermediate was made thirty years ago. Since this discovery, the active site circumstance that enables acylation of the active site serine and fur...

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書誌詳細
出版年:Curr Protein Pept Sci
主要な著者: Fisher, Jed F., Mobashery, Shahriar
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6902449/
https://ncbi.nlm.nih.gov/pubmed/19538154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/138920309789351967
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